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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
21.82
Human Site:
S29
Identified Species:
32
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S29
T
G
H
E
E
K
V
S
V
E
N
F
E
L
L
Chimpanzee
Pan troglodytes
XP_508900
901
98668
S156
T
G
H
E
E
K
V
S
V
E
N
F
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
S29
T
G
H
E
E
K
V
S
V
E
N
F
E
L
L
Dog
Lupus familis
XP_854926
772
85603
S29
T
G
N
E
E
K
V
S
V
E
N
F
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S29
T
G
H
E
E
K
V
S
V
E
N
F
A
L
L
Rat
Rattus norvegicus
Q63531
735
82865
D58
K
A
G
S
E
K
A
D
P
S
H
F
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S27
N
E
V
T
F
N
F
S
L
P
S
T
I
E
D
Chicken
Gallus gallus
Q5F3L1
789
89022
G35
T
G
H
A
E
K
V
G
I
E
N
F
E
L
L
Frog
Xenopus laevis
P10665
733
82620
D58
K
E
G
S
E
K
A
D
Q
S
D
F
V
L
L
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
D63
K
E
G
C
E
K
A
D
P
S
Q
F
E
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S257
L
Y
S
D
E
A
V
S
L
N
D
F
K
I
I
Honey Bee
Apis mellifera
XP_395099
910
102507
R60
D
I
D
D
F
D
M
R
D
F
N
E
P
A
P
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
A27
L
R
V
L
G
K
G
A
Y
G
K
V
F
L
V
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
N31
F
L
V
R
K
V
G
N
H
N
Q
G
K
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
D18
L
G
R
S
K
E
D
D
G
S
S
E
D
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
40
N.A.
6.6
80
33.3
40
N.A.
26.6
6.6
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
46.6
N.A.
20
86.6
40
40
N.A.
66.6
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
7
19
7
0
0
0
0
7
7
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
13
0
7
7
25
7
0
13
0
7
0
7
% D
% Glu:
0
19
0
32
63
7
0
0
0
38
0
13
44
13
0
% E
% Phe:
7
0
0
0
13
0
7
0
0
7
0
63
7
0
0
% F
% Gly:
0
44
19
0
7
0
13
7
7
7
0
7
0
0
0
% G
% His:
0
0
32
0
0
0
0
0
7
0
7
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
0
0
0
7
7
7
% I
% Lys:
19
0
0
0
13
63
0
0
0
0
7
0
13
0
0
% K
% Leu:
19
7
0
7
0
0
0
0
13
0
0
0
0
69
57
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
7
0
7
0
13
44
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
13
7
0
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
13
0
0
0
0
% Q
% Arg:
0
7
7
7
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
19
0
0
0
44
0
25
13
0
0
0
0
% S
% Thr:
38
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
19
0
0
7
44
0
32
0
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _